Mild COVID-19 is uncommon in babies

A recent study found that among newborns less than 28 days, severe COVID-19 accounted for 8% of cases.

An uncommon occurrence of COVID-19 can result in serious illness in newborns, according to a recent study.

The prevalence of COVID-19 is substantially lower in children under the age of four, accounting for just about 3% of cases in the US. This has been explained by the natural defensive mechanisms that exist in young children.

Neonatal COVID-19 frequently has minimal symptoms and a favorable outcome. Newer varieties, however, are now very contagious, which is why the prevalence of infections in newborns is increasing.

Researchers conducted a cross-sectional study across the United States to examine the incidence, regional distribution, severity, aspects of presentation, and clinical outcomes of newborn COVID-19.

The Cerner Real-World Database, which includes information from more than 120 American health systems, was used to compile the statistics. The study included all neonates diagnosed with COVID-19 between March 1, 2020, and February 28, 2021, who were younger than 28 days old.

The incidence of COVID-19 infection, the incidence of severe illness, the regional distribution of infection, and the type of treatment received were among the outcomes monitored. Any instance that had symptoms from 2 of the 3 categories was considered severe. The following symptoms were listed in the first category: a fever of more than 37.5 degrees Celsius, apnea, cough, tachypnea, respiratory distress or recession, the need for supplementary oxygen, and vomiting or diarrhea.

The second category of symptoms includes any combination of low lymphocyte count, low white blood cell count, and elevated C-reactive protein levels. An abnormal chest x-ray was used to measure the third group.

918 interactions out of 1,007,269 were found to be COVID-19 positive. Severe COVID-19 patients made up about 8% of these cases. Compared to female patients, male patients had a higher percentage of severe cases. For mild instances, the median age at hospital admission was 15 days, compared to 11 days for normal cases.

The researchers anticipated that COVID-19 incidence occurred most frequently in newborns shortly after delivery because only 209 patients had their manner of delivery documented. Severe COVID-19 was more likely to develop in low birth weight neonates than non-severe COVID-19. The comorbidity rate in severe patients was about 47%.

At birth, neonates frequently exhibited no symptoms. The most frequent early signs were tachypnea and fever, and pneumonia was seen in roughly 28% of newborns with severe illness.

The findings showed low but not zero incidences of severe COVID-19 and neonatal death. Researchers suggested more investigation into the impact of congenital defects on COVID-19.

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