Covid Killed More People in US than HIV/ADIS did in 40 Years

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According to a news source, Covid-19 has become the deadliest pandemic in US history, killing more deaths than HIV/AIDS has taken in the last 40 years.

According to an article released on Friday by The National website, the US government’s original reaction to HIV/AIDS and Covid-19 was “denial and indifference.”

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According to the research, when AIDS broke out in communities across the United States in the early 1980s, the federal government turned a blind eye and even cut funding for public health agencies.

When the Covid-19 epidemic was first announced in the United States, the White House downplayed the dangers, describing it as “normal flu.”

Minority groups and impoverished areas have been disproportionately affected by both crises, according to the research.

As of Saturday, the Covid-19 epidemic had killed a total of 735,374 individuals in

Background

It’s unknown whether HIV infection is linked to a higher risk of COVID-19-related death. In a large-scale population-based study in England, we wanted to look at this link.

Methods

A retrospective cohort analysis was conducted. We used the OpenSAFELY platform to analyze routinely gathered electronic primary care data linked to national death registries on behalf of NHS England. We included all persons (18 years and older) who were alive and in follow-up on February 1, 2020, and who had at least one year of continuous registration with a general practitioner prior to that date. People with HIV infection who had a primary care record were compared to people who did not have HIV.

COVID-19 death was the result, which was characterized as the presence of International Classification of Diseases 10 codes U07.1 or U07.2 on the death certificate. The link between HIV infection and COVID-19 death was estimate using Cox regression mode that were first adjust for age and sex, then for index of multiple deprivation and ethnicity, and finally for a wide range of comorbidities. To investigate effect modification by age, sex, ethnicity, comorbidities, and calendar time, interaction variables were introduced.

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Results

There were 17 282 905 adults in total, with 27 480 (016%) with HIV. HIV-positive people were more likely to be male, of Black ethnicity, and from a less affluent area than the general population. During the study period, 14 882 COVID-19 fatalities occurred, with 25 of those being HIV positive. After controlling for age and sex, HIV-positive people had a greater risk of COVID-19 death than HIV-negative people: hazard ratio (HR) 290 (95 percent confidence interval 196–430; p00001) After accounting for deprivation, ethnicity, smoking, and obesity, the link was reduced, but the risk remained high: adjusted HR 259 (95 percent CI 174–384; p00001). There was some indication that the link was stronger among Black people: HR 431 (95 percent CI 242–765 versus 184 (103–326 in non-Black persons) (p-interaction=0044).

Interpretation

COVID-19 mortality appears to be higher in HIV-positive people in the United Kingdom. As the pandemic response unfolds, targeted measures should be explored to meet this increased risk.

Funding

Wellcome, the Royal Society, the National Institute for Health Research, the National Institute for Health Research Oxford Biomedical Research Centre, the UK Medical Research Council, and Health Data Research UK are among the organizations that have provided funding.